CONTRALATERAL PROPHYLACTIC MASTECTOMY: A CURRENT LITERATURE REVIEW

MACHADO, L.N. (Pontifícia Universidade Católica de Goiás), MACHADO, J.N. (Pontifícia Universidade Católica de Goiás), PEQUENO, L.S. (Pontifícia Universidade Católica de Goiás), RINCON, M.D.R (Pontifícia Universidade Católica de Goiás), GOMES, J.C.P (Ponti

Pontifícia Universidade Católica de GoiásOBJECTIVES:To carry out a literature review about the increase in the rate of contralateral prophylactic mastectomy (CPM) to treat unilateral breast cancer in women with no genetic predisposition for the development of this disease, highlighting the main reasons for the choice of this treatment and its benefits. METHODOLOGY:A bibliographic survey was implemented on the subject in the Capes Portal databases and in PubMed, the inclusion criteria of the articles were: full availability; published in the period of 2016 to 2017; in Portuguese and English; 23 articles were selected. RESULTS:Most of the studies show that due to the fear of a second breast cancer, subsequent medical visits, invasive treatments, such as surgery and chemotherapy, and concern about the symmetrical appearance, patients are taking on more proactive roles when choosing CPM. It is a fact that these women are not responding to evidence-based recommendations, which is often because of the lack of discussion between the mastologist and the patient. In addition, in women without a BRCA1 or BRCA2 mutation, there is a survival benefit of less than 1% in 20 years for patients with stage I breast cancer. Besides, the benefit was minimal for those with no family history of second degree or stage II and III. Despite this, patients are often determined to pursue this course, changing surgeons or hospitals, in order to achieve CPM CONCLUSION:Based on the analysis of the selected articles, the studies point to the need for a critical evaluation on the increasing use of CPM and an approach to the psychosocial factors that direct women’s preferences for this procedure. Thus, there is a need for studies that include the importance of following medical recommendations based on scientific evidence and showing the relevance of educational information by clinicians on the indications for CPM.breast cancer, contralateral prophylactic mastectomy, genetic predisposition