BREAST CANCER RISK PERCEPTION IN WOMEN REFERRED TO A HIGH RISK BREAST CANCER CLINIC AND THE ASSOCIATION WITH SOCIODEMOGRAPHIC FACTORS, PERSONAL AND FAMILY HISTORY AND CALCULATED OBJECTIVE RISK.

Patricia Kajikawa, Gabriel Y. Ikejiri, Nicoli S. de Azevedo, Gislaine A. F. Carvasan, Natalie Rios Almeida, Tamara P. de Oliveira, Renato Z. Torresan, César C. dos Santos

Objectives: the study intended to estimate breast cancer risk perception in women referred to a brazilian specialized High Risk Clinic for breast cancer and measure the association between perception risk with sociodemographic, personal and family factors and then we analyzed if the risk perception was associated with the objective risk calculated with Gail and Tyrer-Cuzick tools, currently used to estimate objective breast cancer risk. Methods: There were included women referred to High Risk Breast Cancer Clinic in Women’s Hospital in State University of Campinas, from December 2014 to July 2015. We collected sociodemographic data (age, education level) and history of prior breast biopsy with atypical lesions and family history of breast cancer. The lifetime breast cancer risk was calculated with Tyrer-Cuzick and Gail tools and we analysed the risk perception with notes ranging from 0 to 10. Then, it was analysed the association between perception risk and the different variables with Wilcoxon test. Results: the women were 41.7 years mean age and almost half (48%) concluded just the primary education. The lifetime risk of breast cancer was 29.9% calculated by Tyrer-Cuzick and 20.6% by Gail. The average score for risk perception was 5.9 and it was not related to age, education, presence of precursor lesions or family history of breast cancer. There is no association between subjective risk and the objetive risk calculated by two models Tyrer-Cuzick and Gail. Conclusion: these results evidence that women at high risk breast cancer must be properly oriented with a multidisciplinar team because the subjetive risk estimated in this study have no association with age, education, presence of precursor lesions, family history and objetive risk estimated with Gail and Tyrer-Cuzick tools