Evaluate the incidence of breast carcinoma in situ on patients attended at the Dr Arnaldo Vieira de Carvalho Cancer Institute from 2006 to 2012
Biological behavior of breast carcinoma in situ from January 2006 to December 2012
Fábio F. O. Rodrigues, Etiénne A. Bastos, Laís A. Inaba, Eveline A. Silva, Rodrigo M. Silva, Carlos E. Fristachi
Instituto do Câncer Doutor Arnaldo Vieira de Carvalho
Objectives: Evaluate the incidence of breast carcinoma in situ on patients attended at the Dr Arnaldo Vieira de Carvalho Cancer Institute from 2006 to 2012. Methods: A longitudinal study was performed, descriptive type, retrospective, of patients with breast carcinoma in situ attended at ICAVC in Sao Paulo; data were analyzed on the data base of Microsoft Excel@. Results: Were evaluated 267 patients attended at the mastology outpatient clinic, of wich 19 (7,1%) presented a diagnosis of breast carcinoma in situ by the core needle biopsy, being 13 (5%) histologically confirmed at the biopsy of the surgical part, of these 5% presented lobular breast carcinoma in situ (CLIS), two (10%) of the patients with carcinoma in situ presented recurrence, both with invasive component tumor, with hormone receptor positive status and HER-2 positive with high rates of KI67, one patient underwent mastectomy and adjuvant chemotherapy and the other one underwent chemotherapy only, since the first surgical approach was mastectomy; none of these patients presented distant-metastasis until now. Conclusion: With our study, it was observed that the incidence of breast carcinoma in situ at ICAVC was of 7,1%, being compatible with the prevalent incidence of current literature; in addition, it is understood that the presence of breast carcinoma in situ is a marker of risk for invasive carcinoma in relapse.