INFILTRATING DUCTAL BREAST CARCINOMA: A STUDY OF THE CLINICAL PROFILE OF PATIENTS OF THE BRAZILIAN UNIFIED HEALTH SYSTEM

Ana C. M. Magalhães, Bárbara L. Oliveira, Brenda B. M. Mendes, Matheus F. M. Maia, Rayssa O. Glória, Fabiana C. Q. S. Anjos.

Institution: Centro Universitário UNIRG – Gurupi – TOObjective: To analyze the clinical profile of patients with ductal carcinoma of the breast, compare it with the prevalence of other malignant mammary neoplasms, emphasizing the importance of clinical breast examination. Methodology: A cross-sectional study of the histopathological examinations of women performed in Distrito Federal between January/2010 and July/2015 and registered in the Breast Cancer Information System (SisMama). The predominant age group, the histological grade, the form of lesion detection and the clinical size of the ductal carcinomas were evaluated. Chi-square test was performed with 5% significance. Results: In the analyzed period, 2.571 histopathological examinations of the breast were performed, of which 1.114 were malignant. There was a predominance of infiltrating ductal breast carcinomas (IDBC), accounting for 814 cases (73%), while intraductal carcinomas “in situ” accounted for 8.6% (n=96) and invasive lobular carcinomas (ILC), 5.2% (n=58). In the analysis of patients with IDBC, it was observed that the age group of 40-59 years was responsible for 54.17% (n=441), confirming statistical significance according to prevalence (p<0.05). Histological grade II was the most prevalent in histopathological examination (49%). The detection of IDBC was mostly by palpable clinical examination of the breast (80%). Regarding theclinical size of ductal carcinomas, lesions of 2-5 cm (52.57%) were predominant. Non-palpable lesions were less representative (3.56%). Conclusion: Statistically, there is an association between the age group and the prevalence of IDBC. Acoording to the Ministry of Health, this neoplasm is observed in more than 90% of the cases, while in the present study was obtained a lower rate (73%), followed by the ILC with 8,6%, following the national trend of 5 to 10%. Considering that breast cancer is the most common in Brazil and in the world, it is extremely important to perform the clinical examination associated with mammographic screening in order to detect early lesions.breast cancer, ductal carcinoma, lobular carcinoma.